Evaluation of IL _6 and TNFα in serm levels associated with acinetobacter baumannii infection in AL Diwaniya province patients

doi:10.29350/qjps.2025.190622

Evaluation of IL _6 and TNFα in serm levels associated with acinetobacter baumannii infection in AL Diwaniya province patients

https://doi.org/10.29350/qjps.2025.190622

Volume 30, Issue 2
Autumn 2025

Pages 69-82

Abstract

Acinetobacter baumannii is an important highly pathogenic microorganism with have a high levels of antibiotic resistance. and its extraordinary ability to develop additional resistance through the selection of chromosomal mutations and acquisition of resistance genes. In recent years, strains widely disseminated in hospitals throughout the world is being in the “critical” category of the WHO's priority pathogens list for research and development of new antibiotics.
which has caused a hike in nosocomial infection. The diminishing spectrum of treatment against these pathogens demands an alternative realm of treatment. One such nosocomial pathogen, Acinetobacter baumannii is known to cause pneumonia, blood stream infection, urinary tract infections, especially affecting immunocompromised individuals. Due to indiscriminate use of antibiotics, these pathogens have gained resistance to major classes of antibiotics through mutation and horizontal gene transfer via mobile genetic elements such as plasmids, transposons and integrons.