Breast cancer is one of the most generic lethal illnesses affecting women and stays a first-rate public fitness subject because of its profound effect on survival results and average exceptional of life. In advanced stages, the disorder frequently calls for in depth healing procedures, which includes surgical intervention, chemotherapy, and radiotherapy. The mechanisms underlying breast most cancers improvement involve multifaceted interactions between genetic predisposition, hormonal law, environmental affects, and immune machine dysfunction, all of which contribute to tumor initiation and progression.The goal of the existing examine is to analyze the adjustments in selected hematological and immunological parameters in ladies with breast cancer, with unique emphasis on comparing the systemic results associated with distinctive treatment modalities. A general of one hundred twenty contributors were enrolled and categorised into 3 businesses: forty patients undergoing chemotherapy, 40 patients receiving radiotherapy, and forty reputedly healthy women who served as a control institution. Participants had been recruited from Al-Diwaniyah General Hospital between November and December 2025, and diagnosis became hooked up by using oncology specialists based on scientific assessment supported by using laboratory and imaging findings .Venous blood samples were collected for complete blood count (CBC) analysis as well as evaluation of renal and liver function indicators. Comparative statistical analyzes were performed to identify differences between study groups and to clarify the extent to which chemotherapy and radiotherapy affect biological and systemic parameters...